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ARTICLE | Emerging Company Profile

Archon: Tuning antibodies through geometry

Latest spinout from David Baker’s IPD rescuing failed mAbs by forcing them into cage-like structures for better biodistribution, target engagement

November 15, 2024 12:02 AM UTC

Archon is packing antibodies into computationally designed geometries to better control their activity, with the goal of addressing well-understood targets failed by free mAbs.

The company, which emerged from stealth Oct. 30 with a $20 million seed round led by Seattle-based Madrona Ventures, is the latest in a long line of spinouts from University of Washington’s Institute for Protein Design (IPD), which is helmed by 2024 Nobel Prize in Chemistry winner David Baker...