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BioCentury
ARTICLE | Product Development

Exosomes are finding new life as the field solves for manufacturing

Can exosomes step in as delivery vehicles where LNPs fall short?

April 3, 2025 12:08 AM UTC

The sky is starting to clear around exosome therapies after a series of setbacks and technical hurdles raised doubts about the technology. As companies refine manufacturing methods to ensure reliability, reproducibility and scalability, exosomes are coming into focus as delivery vehicles that may bring therapeutic payloads to a range of tissues not yet addressed by LNPs.

This next generation of exosome technology is pivoting from using natural exosomes to engineered versions that are optimized for selective tissue targeting, creating new opportunities. ...

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