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ARTICLE | Distillery Therapeutics

Overexpressing ANXA2 or MPP1 for glaucoma

BC Staff
October 7, 2022 6:37 PM UTC

Increasing the activity of the cell membrane proteins ANXA2 or MPP1 in retinal ganglion cells could help treat glaucoma by stimulating optic nerve regeneration. A retrograde tracing technique to isolate regenerating and non-regenerating retinal ganglion cells for transcriptomic analysis identified multiple genes that potentiate the regenerative effects of PTEN deletion following optic nerve injury, including ANXA2 and MPP1...

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