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BioCentury
ARTICLE | Product R&D

Cutting through resistance

How Locus Biosciences is using CRISPR-Cas3 to tackle antibiotic resistance

Lauren Martz, Senior Writer
August 31, 2017 5:34 PM UTC

Most companies employing CRISPR-Cas9 for therapeutics are using it to edit human cells, but Locus Biosciences Inc. is betting the lesser-known CRISPR-Cas3 system will do a better job of treating bacterial infections and could be the long-sought solution to antibiotic resistance.

The company was launched two years ago to develop an antimicrobial platform that turns bacteria's natural CRISPR-Cas3 defense system against itself to eliminate specific pathogenic species while sparing human cells and the microbiome. ...

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BCIQ Company Profiles

Locus Biosciences Inc.