BioCentury
ARTICLE | Product R&D

Mapping microbiome manufacturing

Why making microbiome drugs will require reinventing bacterial manufacturing

March 1, 2019 3:23 AM UTC

Microbiome companies have been squeezed by the scarcity of contract manufacturers willing to work with tough bacterial strains. While contractors are starting to engage, it could take a big clinical win for them to fully take the plunge.

Manufacturing is one of the biggest bottlenecks faced by microbiome companies. Despite decades of experience growing bacteria to produce biologics, the biotech industry is ill-equipped to produce live bacterial therapies. ...