BioCentury
ARTICLE | Targets & Mechanisms

Oral insulin innovation

How preclinical technologies could make oral insulin cheap enough to compete

March 8, 2019 1:56 AM UTC

While clinical data suggest an oral insulin product may finally be within reach, the technology struggles to compete with injectables on price and efficacy. A handful of academics and companies are pushing preclinical innovation in formulation and device design, aiming to solve the commercial conundrum.

Despite numerous setbacks over at least 50 years, the allure of an oral insulin product that eliminates frequent injections and reduces the risk of dangerous hypoglycemic episodes has continued to spur research in the field...