An O. Henry ending?

Street watchers lost no time getting down to brass tacks with Genzyme Corp. Chairman, President and CEO Henri Termeer at last week's 28th Annual J.P. Morgan Healthcare Conference in San Francisco.

One of the early questions at the company's breakout session was why he should continue as chief executive in the wake of the company's manufacturing difficulties. Termeer cited his accomplished during his 25 years at the helm, while also accepting responsibility for "this interruption."...