BioCentury
ARTICLE | Discovery & Translation

AACR brings new modalities, new targets to glioblastoma

BioCentury identifies new CAR T cell designs, ADCs and other modalities, plus 37 preclinical targets for the challenging indication

April 9, 2024 9:34 PM UTC

The cancer breakthroughs of the past decade that transformed treatment of indications ranging from melanoma to lymphoma have left little mark on glioblastoma. Research presented at AACR this year aims to change that. The conference features a series of studies that apply new therapeutic modalities and targets to the challenging indication.

A cluster of abstracts released ahead of the American Association for Cancer Research (AACR) annual meeting, which runs April 5-10, builds on early but encouraging clinical evidence that CAR T cell therapies may find an application in high-grade gliomas. ...