BioCentury

Current Editions

December 16, 2024
Finding opportunity in chaos: Editor’s Commentary

How biopharma can navigate Trump 2.0

Editor's Commentary

The VEGF x PD-(L)1 pipeline is growing and TNBC may benefit

BioNTech gearing up to advance BNT327 to Phase III for triple-negative breast cancer after promising Phase II survival data

Product Development

VC fundraising in a post-‘supercycle’ era: a Perspective

Some firms are no longer making their latest funds their largest; others may follow

Editor's Commentary

Biosecure setback amid lawmakers’ push to reduce reliance on China

Defense bill places biotech under national security umbrella

Politics, Policy & Law

Preclinical IPO scorecard: 2020-24

Riskier bets deliver returns comparable to clinical counterparts

Finance

Product Development

Only the paranoid survive, and the CEO’s paradox, from Aoife Brennan

How CEOs are managing through uncertainty, and why ‘boring’ naked mAbs are the smart move in one field

Gene and base editors deliver on fetal hemoglobin expression: ASH24

Editas, Beam report updates on sickle cell genetic therapies at this year’s ASH meeting

Data Byte

November’s FDA approvals include Autolus’ CD19 CAR T 

Plus: BridgeBio’s Attruby approved for ATTR-CM, PTC’s gene therapy for AADC deficiency, and Gilead withdrew Trodelvy for urothelial cancer

BridgeBio, Geron follow U.S. approvals with nods from EMA’s CHMP

November meeting highlights also include a pair of firsts for rare genetic diseases, and label expansions for eight approved drugs

Discovery & Translation

Science Spotlight: snoRNA control of protein secretion, plus dual agonists for obesity

BioCentury’s roundup of translational innovations also includes an Arkuda-J&J granulin gene therapy

Deals

Nvelop, Chroma merger creates opportunity for targeted epigenome editors

Nvelop CEO Jeff Walsh will lead nChroma, which has $75M in new funding and a lead for HBV

Frustrated by IRA, Relay out-licenses ‘NDA-ready’ program to Elevar

Also in BioCentury’s Deals Report, a trio of biotech deals by GSK, and more

Finance

Techbio VC Dimension upsizes for $500M second fund; PE firm takes stake in Andera

In BioCentury’s Venture Report: Fundings for Citryll, Angitia, Tasca, Veradermics and more

Data spells money for a quintet of biotechs

NewAmsterdam’s CETP readout leads to week’s largest follow-on

Biopharma Stock Performers

Use BioCentury's interactive dashboard to view top-performing biopharma stocks for the day and the week.

BioCentury ISSN 1097-7201