BioCentury

Current Editions

November 11, 2024
Prepping for Trump

The biopharma industry faces opportunities, threats and a lot of food for thought

Politics, Policy & Law

Are PD-1 agonists finally on the verge of impacting inflammation?

Eli Lilly is out of the race, but other companies believe they have differentiated products

Product Development

The ethics of Alzheimer's trials: more to the story 

Companies, academics, advocates push back on claims they should have disclosed genotype to Alzheimer's trial participants

Product Development

Myths and misperceptions — industry’s stumbling blocks

What are biotechs, pharmas and academics getting wrong about each other?

Editor's Commentary

Probe intensifies spotlight on AstraZeneca in China

Global pharmas and local biotechs weigh fallout of investigation into AZ China head

Politics, Policy & Law

Product Development

The evolving picture of ARIA risk and APOE4 status in Alzheimer’s

As data on amyloid-targeting drugs have emerged, pressing questions—and answers—about their leading safety concern have come into focus

Alzheimer’s roundup: Clinical progress and setbacks at CTAD

Readouts showcase promise of Roche’s brainshuttle; plus mixed results from Lilly, Lexeo and Anavex

Two upcoming readouts could shape the market for κ-opioid antidepressants

Emerging class could find niche among patients whose major depressive disorder includes symptoms of anhedonia

Viking continues push for VK2735 as best in class in obesity

Dual GIP/GLP-1 agonist shows highly competitive efficacy, safety, dosing flexibility; although oral dose could limit commercial supply

Arcus data the latest twist in the TIGIT story

BioCentury’s Clinical Report also analyzes the impact of a patient death in Beam’s trial, plus data from Cogent, Disc, Essa and Novo

Editor's Commentary

China biotech and the bear: a Perspective

Deal-making with the West offers a path through uncertain times, but in what position will China biotechs emerge from the bear?

Data Byte

FDA’s October approvals include the first CLDN18.2 mAb

Plus: Agency approves Pfizer’s hemophilia A and B mAb, and label expansions for five products

Three FDA advisory committees in November

Panels to discuss Andexxa’s full approval, medical devices that use generative AI, and the REMS for clozapine

Discovery & Translation

New frontiers in extracellular protein degradation

Six papers detail improved ways to degrade cell-surface cancer proteins through the lysosome

Science Spotlight: Multi-epitope antivirals, metastatic transition, and more

BioCentury’s roundup of translational innovations also includes a study from Amgen and a newco spotlight

Deals

With Eylea rival in clinic, once-stealthy Kalaris finds public path via merger

Samsara-backed start-up launched by former Genentech colleagues picks AlloVir as vehicle to reach NASDAQ

Dealmaking in a drought crowns Gracell, Proteologix BayHelix winners

M&A and licensing deals feature prominently in nearly all categories of this year’s BayHelix Awards

Finance

Neurogene draws $200M PIPE ahead of next week’s Rett syndrome data

In BioCentury’s Finance Report: Travere’s follow-on, CrossBridge’s seed round among few fundings during quiet election week

Biopharma Stock Performers

Use BioCentury's interactive dashboard to view top-performing biopharma stocks for the day and the week.

BioCentury ISSN 1097-7201