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BioCentury

Current Editions

March 24, 2025
PhRMA, BIO fighting tariffs

Trump's threat to impose 25% pharma tariffs has alarmed biopharma companies, spurred talk of mitigation strategies

Politics, Policy & Law

Tempus aims for precision in complexity

With clinical records, patient samples and images in the millions, the diagnostics and data company is betting precision medicine can go multimodal

Product Development

Lundbeck’s next chapter: from psychiatry to rare neuro

Leaving past limitations behind, Danish pharma widens its technology aperture to brain shuttles, AI and more  

Product Development

Solving CNS delivery will open big doors for epigenome editing: a Perspective

Epigenome editors could shine in neurology indications not served by other modalities — but only if companies invest in delivery

Editor's Commentary

Product Development

Beating the odds by sticking to the serial strategy — Vertex’s Altshuler on The BioCentury Show

How Vertex is translating its success from CF into new areas, picking indication by indication, while leveraging AI

Emerging Company Profile

Trio: Introducing two new types of dual-targeting antibodies for cancer

San Francisco Bay Area biotech has two antibody platforms designed to improve on the potency and safety of bispecifics

Market Access

Patient death resurfaces safety concerns for Sarepta’s gene therapy

But it’s unclear that market access will be affected

Data Byte

FDA’s new and supplemental approvals in February

Springworks gets priority review voucher for Gomekli, first NovoLog biosimilar reaches market, and more

CVRs heavily discounted in biopharma M&A deals: Data Byte

After a takeout is announced, the target company’s share price hews much closer to the deal price without the CVR than with it

Wuxi stocks bounce back as Biosecure threat fades

Shares of Wuxi Apptec and Wuxi Biologics are closing in on pre-Biosecure levels

FCRN inhibitor sales: Vyvgart dominates market

Vyvgart sees strong growth with CIDP approval

Discovery & Translation

Science Spotlight: TGFβ drives long COVID inflammation via EBV

BioCentury’s roundup of translational innovations also includes boosting T cell antitumor activity via fructose, and a new Parkinson’s risk gene

Regulation

Amvuttra’s label expansion lifts Alnylam toward five-year goals

Non-GAAP profitability in sight as RNAi therapeutic adds cardiomyopathy indication alongside previous amyloidosis approval

Politics, Policy & Law

Short window to halt FDA brain drain

Trump administration personnel policies are driving experienced staff to quit

Finance

Strategics back Sofinnova Partners’ ‘pan-European’ accelerator in €165M fund

Following eight-year ‘pilot experiment’ in Italy, the firm’s Biovelocita now builds companies across Europe

With Medicxi’s backing, Curevo takes aim at Shingrix with $110M series B

Former GSK vaccines head Slaoui becomes chairman as Seattle start-up advances shingles shot that may confer tolerability benefit

Maxion, Ampersand, Latigo, Arbor raise private rounds: Finance Report

Plus: SV Health Investors hits $250M goal for second Dementia Discovery Fund

Biopharma Stock Performers

Use BioCentury's interactive dashboard to view top-performing biopharma stocks for the day and the week.

BioCentury ISSN 1097-7201