BioCentury

Current Editions

May 12, 2025
Obesity trend watch: Companies aim for higher quality weight loss

An analysis of the targets companies are pursuing to retain muscle while losing fat

Product Development

SMARCA2: The next big opportunity for degraders?

Targeted protein degraders and selective small molecules face off against SMARCA4-mutant cancers at AACR

Product Development

Can the U.S. turmoil make this Europe’s moment to shine? A Perspective

With U.S. institutions under strain, Europe must act decisively to support innovation and secure a bigger role in biotech’s future

BioCentury Commentary

Insight into ovarian cancer treatment resistance: Literature Dive

Four tumor atlases point to target vulnerabilities and predictive signatures in epithelial ovarian cancers

Discovery & Translation

Product Development

What’s next for biotech in Europe — a Bio€quity preview podcast

Special guests join BioCentury to discuss how industry can navigate the new complexity. Plus: the Belgian biotech ecosystem

Data Byte

FDA approved three new drugs in April

Total CDER approvals stand at 10 so far this year, 50% less than at this time last year

KRAS innovation moves in a degrader direction at AACR 2025

At least 13 companies described preclinical KRAS degraders at the meeting

Novo’s GLP-1s see another 1Q sales dip

Compounded GLP-1s impact 1Q25 sales growth

Discovery & Translation

Science Spotlight: Balancing safety and efficacy with dual TCR/CAR T cells

BioCentury’s roundup of translational innovations also includes microglia replacement for neurological disorders and enhanced mRNA vaccine efficacy 

Regulation

‘Arbitrary’ FDA decision-making puts U.S. innovation at risk, says Soon-Shiong

About-face by FDA on bladder cancer application stuns Immunitybio 

Prasad’s hiring as head of CBER rattles biotech investors

XBI falls as investors, biotech CEOs weigh whether approval bar will rise

Politics, Policy & Law

Pharma in state of alarm as Trump pushes ‘most favored nation’ Medicaid drug prices

Trade associations and biopharma CEOs are mobilizing to oppose the drug pricing policy

Finance

Boehringer Venture’s high risk, high reward strategy enters next phase

How the corporate VC is evolving its portfolio strategy

Earlybird, Sofinnova back Swiss start-up Haya in move toward clinic: Finance Report

Plus: Deerfield raises $600M for next vehicle, Vivo’s refreshed evergreen fund, and more

Biopharma Stock Performers

Use BioCentury's interactive dashboard to view top-performing biopharma stocks for the day and the week.

BioCentury ISSN 1097-7201