BioCentury
ARTICLE | Discovery & Translation

Distillery spotlight: new Alzheimer’s mechanisms from academia

BioCentury’s survey of the 2023 translational literature highlights a cluster of neuron-targeting mechanisms for Alzheimer’s disease 

March 5, 2024 2:04 AM UTC

Neuron-targeting mechanisms for Alzheimer’s disease stood out as a trend among the preclinical therapeutic innovations published in 2023 and captured in BioCentury’s Distillery.

These academic discoveries, each with supporting evidence from patient samples, are a departure from the amyloid-targeting Alzheimer’s therapies on the market, and the neuroinflammation, tau-targeting and metabolism-focused mechanisms that industry stakeholders consider the next big hopes for the disease...