Distillery spotlight: new mitochondrial mechanisms from academia

Insights into how mitochondria are formed, fused, divided or destroyed could guide the next generation of therapeutics that tune mitochondrial activity in disease-relevant cells. 

Mitochondrial biology is increasingly becoming a focus for newco formation and drug discovery. BioCentury’s analysis of companies that raised series A rounds in 2023 identified induction of mitophagy — the degradation of old or dysfunctional mitochondria, which triggers biogenesis of new, healthy organelles — as an emergent technology cluster. ...